No need for sample fixation

Extremely low sample consumption

Measuring affinity (Kd)

Not limited by ligand molecular weight

Samples don't require labeling or fixation

Measuring affinity (Kd)

Reaction enthalpy and entropy changes

Binding site numbers

Unlabeled samples

High throughput

Measuring affinity (Kd)

Binding constant Kon

Dissociation constant Koff

Not limited by sample buffer constraints

High throughput

Melting temperature (Tm)

The intrinsic thermal stability of the target protein

Ligand-target protein interactions

No need for sample fixation

High throughput

Melting temperature (Tm)

The intrinsic thermal stability of the target protein

Ligand-target protein interactions