Fragment-based drug screening involves the identification of small molecule fragments that weakly interact with the target protein using various interaction methods. Subsequently, based on their structural information, these active fragments are optimized to obtain lead compounds with higher activity for the development of new drugs.
Diverse Fragment Libraries
Our diverse fragment libraries are designed to cover a broad chemical space, ensuring high hit rates and efficient identification of binding sites.
Advanced Screening Techniques
Utilizing Enzyme activity experiment, X-ray crystallography, SPR, and other biophysical methods, we can rapidly identify and characterize fragment interactions.
Efficient Fragment Optimization
Through fragment growth, linking, and merging strategies, we transform initial hits into high-affinity lead compounds.
