Crystallization-grade Protein Production

• Gene contrust design
• Protein expression
• Protein purification

Feasibility Test & Frozen sample preparation

• Negative staining TEM: prove homogeneity and complex stability.
• Vit-robot possesses sample to an extremely thin layer of molecular solution that is quickly frozen by liquid ethane.

CryoEM Data Collection

• The highly stable Low-resolution(200kV) and High-resolution(300kV) in-house cryoelectron microscopy provide
  high-throughput, automated data collection.

Structure determination, modeling and refinement

• The three-dimensional reconstruction of macromolecules depends on the average of tens of thousands of particle pictures, in which the data needs to be processed in multiple steps and appropriate computational resources need to be called.