Publications

Atomically precise single-crystal structures of electrically conducting 2D metal-organic frameworks

Nat Mater . 2021 Feb;20(2):222-228. doi: 10.1038/s41563-020-00847-7.

This paper reported crystal structures of 2D π-conjugated MOFs with electrical conductivity, and the atomic-level resolution structures were precisely determined by the cultivation of large single crystals and MicroED techniques.

Structure determination of MicroED in this paper was done by the team of Prof. Junliang Sun, the founder of ReadCrystal.

FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis

Nat Chem. 2020 Jul;12(7):620-628. doi: 10.1038/s41557-020-0467-7.

This paper reported the key steps of active natural product biosynthesis in the traditional Chinese medicine, Moraceae (mulberry), and reported the first monofunctional enzyme catalyzing the intermolecular Diels-Alder reaction existing in nature.

This paper was published in collaboration with the team of Prof. Xiaoguang Lei, the founder of ReadCrystal.

Structural basis of Gs and Gi recognition by the human glucagon receptor

Science . 2020 Mar 20;367(6484):1346-1352. doi: 10.1126/science.aaz5346.

This paper reported the structures of the human glucagon receptor (GCGR) bound to glucagon and distinct classes of heterotrimeric G proteins, Gs or Gi1 which were determined by Cryo-EM SPA.

The researcher who was responsible for the structure determination of GCGR by Cryo-EM SPA in this paper is currently working at ReadCrystal, in charge of the Cryo-EM SPA project.

Single crystal of a one-dimensional metallo-covalent organic framework

Nat Commun . 2020 Mar 18;11(1):1434. doi: 10.1038/s41467-020-15281-1.

In this paper, a single crystal of mCOF was synthesized and its structure was determined by MicroED technique.

Structure determination of MicroED in this paper was done by the team of Prof. Junliang Sun, the founder of ReadCrystal.

3D Electron Diffraction Unravels the New Zeolite ECNU-23 from the "Pure" Powder Sample of ECNU-21

Angew Chem Int Ed Engl . 2020 Jan 13;59(3):1166-1170. doi: 10.1002/anie.201912488.

In this paper, ECNU-23, a novel crystalline high-silica zeolite with 12×8-membered ring (R) channel system is prepared with the aid of the 3D electron diffraction (3D ED) (also called MicroED) technique.

Structure determination of ECNU-23 in this paper was done by the team of Prof. Junliang Sun, the founder of ReadCrystal.

Discovery of Complex Metal Oxide Materials by Rapid Phase Identification and Structure Determination

J Am Chem Soc . 2019 Mar 27;141(12):4990-4996. doi: 10.1021/jacs.9b00093.

This paper presented a strategy to shorten the period of discovery of new complex metal oxide materials by rapid phase identification and structure determination with MicroED techniques, which do not require pure samples or single crystal growth.

Structure determination of MicroED in this paper was done by the team of Prof. Junliang Sun, the founder of ReadCrystal.